Yes, depot is a Scrabble word!
...and is worth 8 points in Scrabble, and 9 points in Words with Friends
depot
Noun
1. Station where transport vehicles load or unload passengers or goods
2. A depository for goods
What Scrabble words can I make with the letters in depot?
5 Letter Words
4 Letter Words
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3 Letter Words
2 Letter Words