Yes, fists is a Scrabble word!
...and is worth 8 points in Scrabble, and 8 points in Words with Friends
fists
Noun
1. A hand with the fingers clenched in the palm (as for hitting)
What Scrabble words can I make with the letters in fists?
5 Letter Words
4 Letter Words
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3 Letter Words
2 Letter Words