Yes, pox is a Scrabble word!
...and is worth 12 points in Scrabble, and 13 points in Words with Friends
pox
Noun
1. A common venereal disease caused by the treponema pallidum spirochete; symptoms change through progressive stages; can be congenital (transmitted through the placenta)
2. A contagious disease characterized by purulent skin eruptions that may leave pock marks
What Scrabble words can I make with the letters in pox?
2 Letter Words