Yes, pyrosis is a Scrabble word!

...and is worth 12 points in Scrabble, and 12 points in Words with Friends

pyrosis

Noun

1. A painful burning sensation in the chest caused by gastroesophageal reflux (backflow from the stomach irritating the esophagus); symptomatic of an ulcer or a diaphragmatic hernia or other disorder

What Scrabble words can I make with the letters in pyrosis?

6 Letter Words

prissy
pyosis

5 Letter Words

pisos
priss
pross
prosy
pyros
spiry
sysop

4 Letter Words

piso
pois
posy
pros
psis
pyro
rips
ropy
rosy
sips
sirs
sops
sori
soys
spry
sris
yips

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Words that can be created with an extra letter added to pyrosis:

O:isosporyG:gossipry