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Yes, pyxie is a Scrabble word!
...and is worth 17 points in Scrabble, and 17 points in Words with Friends
1. Creeping evergreen shrub having narrow overlapping leaves and early white star-shaped flowers; of the pine barrens of New Jersey and the Carolinas
What Scrabble words can I make with the letters in pyxie?
4 Letter Words
3 Letter Words
2 Letter Words