Yes, setoff is a Scrabble word!
...and is worth 12 points in Scrabble, and 12 points in Words with Friends
setoff
Noun
1. Structure where a wall or building narrows abruptly
What Scrabble words can I make with the letters in setoff?
6 Letter Words
5 Letter Words
4 Letter Words
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3 Letter Words
2 Letter Words