Yes, uptake is a Scrabble word!
...and is worth 12 points in Scrabble, and 14 points in Words with Friends
uptake
Noun
1. The process of taking food into the body through the mouth (as by eating)
2. A process of taking up or using up or consuming
What Scrabble words can I make with the letters in uptake?
6 Letter Words
5 Letter Words
4 Letter Words
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3 Letter Words
2 Letter Words