Yes, vowel is a Scrabble word!
...and is worth 11 points in Scrabble, and 13 points in Words with Friends
vowel
Noun
1. A speech sound made with the vocal tract open
2. A letter of the alphabet standing for a spoken vowel
What Scrabble words can I make with the letters in vowel?
4 Letter Words
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3 Letter Words
2 Letter Words