Yes, zygote is a Scrabble word!
...and is worth 19 points in Scrabble, and 19 points in Words with Friends
zygote
Noun
1. (genetics) the diploid cell resulting from the union of a haploid spermatozoon and ovum (including the organism that develops from that cell)
What Scrabble words can I make with the letters in zygote?
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Words that can be created with an extra letter added to zygote:
S:zygotes