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Yes, lexeme is a Scrabble word!
...and is worth 15 points in Scrabble, and 17 points in Words with Friends
1. A minimal unit (as a word or stem) in the lexicon of a language; `go' and `went' and `gone' and `going' are all members of the English lexeme `go'
What Scrabble words can I make with the letters in lexeme?
5 Letter Words
3 Letter Words
2 Letter Words