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Yes, up is a Scrabble word!
...and is worth 4 points in Scrabble, and 6 points in Words with Friends
1. Spatially or metaphorically from a lower to a higher position
2. To a higher intensity
3. Nearer to the speaker
4. To a more central or a more northerly place
5. To a later time
1. Being or moving higher in position or greater in some value; being above a former position or level
2. Out of bed
3. Getting higher or more vigorous
4. Extending or moving toward a higher place
5. (usually followed by `on' or `for') in readiness
7. (used of computers) operating properly
8. Used up