Yes, best is a Scrabble word!

Adverb

1. In a most excellent way or manner

2. It would be sensible

3. From a position of superiority or authority

4. (often used as a combining form) in a good or proper or satisfactory manner or to a high standard (`good' is a nonstandard dialectal variant for `well')

5. Thoroughly or completely; fully; often used as a combining form

6. Indicating high probability; in all likelihood

7. (used for emphasis or as an intensifier) entirely or fully

8. To a suitable or appropriate extent or degree

9. Favorably; with approval

10. To a great extent or degree

11. With great or especially intimate knowledge

12. With prudence or propriety

13. With skill or in a pleasing manner

14. In a manner affording benefit or advantage

15. In financial comfort

16. Without unusual distress or resentment; with good humor

Verb

1. Get the better of

Adjective

1. (superlative of `good') having the most positive qualities

2. (comparative and superlative of `well') wiser or more advantageous and hence advisable

3. Having desirable or positive qualities especially those suitable for a thing specified

4. Having the normally expected amount

5. Morally admirable

6. Deserving of esteem and respect

7. Promoting or enhancing well-being

8. Agreeable or pleasing

9. Of moral excellence

10. Having or showing knowledge and skill and aptitude

11. Thorough

12. With or in a close or intimate relationship

13. Financially sound

14. Most suitable or right for a particular purpose

15. Resulting favorably

16. Exerting force or influence

17. Capable of pleasing

18. Appealing to the mind

19. In excellent physical condition

20. Tending to promote physical well-being; beneficial to health

21. Not forged

22. Not left to spoil

23. Generally admired

Noun

1. The supreme effort one can make

2. The person who is most outstanding or excellent; someone who tops all others

3. Canadian physiologist (born in the United States) who assisted F. G. Banting in research leading to the discovery of insulin (1899-1978)