Yes, prime is a Scrabble word!
...and is worth 9 points in Scrabble, and 11 points in Words with Friends
prime
Verb
1. Insert a primer into (a gun, mine, or charge) preparatory to detonation or firing
2. Cover with a primer; apply a primer to
3. Fill with priming liquid
Adjective
1. First in rank or degree
2. Used of the first or originating agent
3. Of superior grade
4. Of or relating to or being an integer that cannot be factored into other integers
5. Being at the best stage of development
Noun
1. A number that has no factor but itself and 1
2. The period of greatest prosperity or productivity
3. The second canonical hour; about 6 a.m.
4. The time of maturity when power and vigor are greatest
What Scrabble words can I make with the letters in prime?
4 Letter Words
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2 Letter Words