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Yes, tire is a Scrabble word!
...and is worth 4 points in Scrabble, and 4 points in Words with Friends
1. Lose interest or become bored with something or somebody
2. Exhaust or get tired through overuse or great strain or stress
4. Cause to be bored
1. Hoop that covers a wheel
What Scrabble words can I make with the letters in tire?
4 Letter Words
3 Letter Words
2 Letter Words