Yes, zithern is a Scrabble word!
...and is worth 19 points in Scrabble, and 19 points in Words with Friends
zithern
Noun
1. A musical stringed instrument with strings stretched over a flat sounding board; it is laid flat and played with a plectrum and with fingers
What Scrabble words can I make with the letters in zithern?
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Words that can be created with an extra letter added to zithern:
S:zitherns